case study · gene editing therapeutics C O D O N

gene editing, quietly precise.

Codon turns rare-disease genetics into clinical programs. A therapeutics company brand and design language for science that has to read as both rigorous and human.

— specimen 01
chromosomal target 17q21.31
strand orientation 5′ → 3′
edit class guided · double-strand
— the science

Cas9, guided by RNA, makes a single cut.

Codon's platform is built on a quiet truth: gene editing is at its most powerful when it is restrained. One sequence, one cut, one repair. The brand carries that discipline through every surface.

A guide RNA — twenty bases long, a near-perfect match to the target locus — directs Cas9 to a single position in three billion. The enzyme reads, confirms, and cuts. The cell repairs. What changes is precise. What is left is everything else.

The system below — sketched at the level of visible, not literal — anchors every Codon surface: investor decks, regulatory submissions, the patient registry, the lobby glass at HQ.

Cas9 + guide directed cleavage
A · T pairing two hydrogen bonds
edit · repair single-base resolution
the molecule brand artifact
— the pipeline

Three programs, three diseases, one platform.

Codon advances rare-disease therapeutics where the genetics are well-characterised and the unmet need is total. Each program targets a single locus with a single edit.

cdn-101 ● lead

apolipoprotein

target · ANGPTL3 — chr 1p31.3

A single-edit therapy for homozygous familial hypercholesterolemia. Reduces LDL by silencing ANGPTL3 in hepatocytes — durable, one-time treatment.

phase 2 / 4
cdn-204 preclinical

retinal dystrophy

target · RPE65 — chr 1p31.2

Ocular gene editing for Leber congenital amaurosis. Locally delivered, single-injection, restores rhodopsin cycling in retinal pigment epithelial cells.

phase 1 / 4
cdn-307 discovery

sickle haemoglobin

target · BCL11A enhancer

Reactivation of fetal haemoglobin via a precise enhancer disruption. In vivo delivery to hematopoietic stem cells, building on the Vertex / CRISPR Tx blueprint.

phase 0 / 4
platform continuous

delivery library

lipid nanoparticle · AAV

A continuously-improving toolkit of tissue-targeted delivery vehicles. Each new program contributes back into the library; each future program inherits.

type infrastructure
scroll the rail
— the system

One grid. Two typefaces. One molecule.

The visual system reads as scientific without reading as clinical-cold. Editorial spreads, clinical one-pagers, and a patient registry portal share the same restraint.

— display · Archivo 800 codon.
— signal · cyan #7adcef
— outcome · IND filed 14/m months from candidate to first investigational application
— accent · violet #b094d4
— outcome · patient access 62k visitors · patient registry portal · first six months
— warm · counter #d68a64
— ground · indigo #07070d
— what we built Brand identity, logotype, two-typeface system, scientific data-viz language, patient registry portal (concept), print system for investor & regulatory.